Trazodone impurities and related standards
Trazodone is held here as a working collection of 181 reference materials across 30 CAS numbers. 141 of the entries are impurity-type materials of the parent, 19 are salt or counter-ion variants and 9 carry a deuterium label and 5 are nitrosamine analogues. 39 entries carry a verified structure drawing, a coverage of 22%; the rest are listed without a structure rather than with an unverified one. 38 of them sit in tier A or B, meaning the data behind the page is complete enough to be indexed and quoted directly, while 143 remain tier C and are kept for search coverage. Each of these materials is normally supplied with its own chromatographic purity and its own content basis, and the two numbers are not interchangeable. A standard quoted at 98 per cent by area can be materially lower by mass once residual solvent and water are counted, which changes the weight a laboratory has to weigh. A certificate that names the synthetic route the standard was qualified against is more useful than one that only reports purity, since the same impurity can arise from two routes and only one of them will be present in a given product.
Sources: DailyMed (US NLM) - TRAZODONE HYDROCHLORIDE TABLET [APHENA PHARMA SOLUTIONS - TENNESSEE, LLC ].
50 reference standards related to Trazodone held in the RSSE catalogue — pharmacopoeial impurities, non-compendial impurities, metabolites and labelled analogues where available.
In this group: 21 impurity reference standards · 9 stable isotope labelled standards · 6 fine chemicals · 6 general reference standards. CAS numbers are listed for 50 of 50; 50 entries carry a structure drawing.
On this page
50 reference standards
All entries — structure, identifiers and pack sizes
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Trazodone
IN STOCKRS-U087209 -
Trazodone hydrochloride
IN STOCKRS-U087240 -
Trazodone BP Impurity C
IN STOCKRS-T187001 -
Trazodone EP Impurity H diHCl
BACK ORDERRS-T187008 -
Trazodone EP Impurity J (Hydrochloride)
IN STOCKRS-T187002 -
Trazodone Hydrochloride-Impurity H (Dihydrochloride Salt)
BACK ORDERRS-Z401G0H -
1-(3-Bromophenyl)piperazine Hydrochloride
IN STOCKRS-I012276 -
1-(3-Bromopropyl)piperazine
IN STOCKRS-I516359 -
1-(3-Chloro-4-ethylphenyl)piperazine Hydrochloride
CUSTOM SYNTHESISRS-U006606 -
1-(3-Chlorophenyl)-4-(3-chloropropyl)piperazine hydrochloride
IN STOCKRS-C003153 -
1-(3-Chlorophenyl)-piperazine
IN STOCKRS-Z412RUH -
Trazodone EP Impurity L Hydrochloride
IN STOCKRS-P001994 -
1-(3-Chlorophenyl)piperazine-d8
IN STOCKRS-I098076 -
1-(3-Chlorophenyl)pyrrolidine
IN STOCKRS-Z003IE3 -
1-(3-chloropropyl)-4-(3,4-dichlorophenyl)piperazine
IN STOCKRS-P001004 -
1-(3-chloropropyl)-4-phenylpiperazine
CUSTOM SYNTHESISRS-Z393NKC -
1-(4-Bromophenyl)piperazine Hydrochloride
IN STOCKRS-Z004X8M -
1-Bromo-3-chloropropane-13C3
IN STOCKRS-I096034 -
2-(3-aminopropyl)-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one
CUSTOM SYNTHESISRS-P018094 -
2-(3-Bromopropyl)-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one
IN STOCKRS-P003265 -
3,4-Dichloro Trazodone-d6 Hydrochloride
BACK ORDERRS-T187003 -
3-(4-(3-Chloropropyl)piperazin-1-yl)propan-1-ol
IN STOCKRS-U071853 -
4'-Hydroxytrazodone b-D-glucuronide
BACK ORDERRS-Z401J8V -
4-chloropyridine
IN STOCKRS-U090132 -
4’-Hydroxy Trazodone-d6 Benzyl Ether
BACK ORDERRS-I105127 -
Trazodone Hydrochloride Impurity 15 (Trazodone Hydrochloride EP Impurity K)
IN STOCKRS-U016705 -
Diethanolamine (DEA)
IN STOCKRS-I097028 -
Etoperidone-d8 Hydrochloride
BACK ORDERRS-I110093 -
m-chlorophenylpiperazine D8
IN STOCKRS-I094454 -
Myristic Acid Diethanolamide
IN STOCKRS-Z401KPR -
Trazodone D6
IN STOCKRS-T187004 -
Trazodone Impurity QZT-IM-2-Z4 HCl
IN STOCKRS-T187007 -
Trazodone-[d6] hydrochloride
IN STOCKRS-I118024 -
Trazodone Impurity 12
BACK ORDERRS-T187009 -
Trazodone Impurity 28 HCl salt
IN STOCKRS-T187006 -
Trazodone Impurity 36
CUSTOM SYNTHESISRS-I001AUQ -
Trazodone impurity 41
BACK ORDERRS-I001B68 -
Trazodone impurity 42
BACK ORDERRS-I001736 -
Trazodone impurity 47
IN STOCKRS-I001468 -
Trazodone impurity 55 HCl
IN STOCKRS-I001542 -
Trazodone Impurity 58
IN STOCKRS-T187010 -
Trazodone Impurity 71
IN STOCKRS-I001AVI -
Trazodone Impurity 74 HCl
CUSTOM SYNTHESISRS-T187012 -
Trazodone impurity 77
CUSTOM SYNTHESISRS-Z401DH1 -
Trazodone impurity 78
IN STOCKRS-I001535 -
Trazodone Impurity 105
CUSTOM SYNTHESISRS-I001ARU -
Trazodone Impurity 107
IN STOCKRS-I001BOP -
Trazodone Impurity 111
IN STOCKRS-T187005 -
Trazodone Impurity 112
CUSTOM SYNTHESISRS-T187011
50 reference standards
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![Chemical structure of 1-(3-Chlorophenyl)-4-(3-(3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)propyl)piperazine 1-oxide](/structures/w4/DUMIFIQJLKHMRQ-UHFFFAOYSA-N.webp?v=9)









![Chemical structure of 2-(3-aminopropyl)-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one](/structures/w4/QFSWXZCTAOENQY-UHFFFAOYSA-N.webp?v=9)
![Chemical structure of 2-(3-Bromopropyl)-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one](/structures/w4/CUWHDJVYWOQIGD-UHFFFAOYSA-N.webp?v=9)












![Chemical structure of Trazodone-[d6] hydrochloride](/structures/w4/OHHDIOKRWWOXMT-BHIQTGFXSA-N.webp?v=9)














