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Tolmetin impurities and related standards

Tolmetin is held here as a working collection of 16 reference materials across 10 CAS numbers. 7 of the entries are impurity-type materials of the parent, 3 are salt or counter-ion variants and 2 carry a deuterium label. 10 entries carry a verified structure drawing, a coverage of 62%. 9 of them sit in tier A or B, meaning the data behind the page is complete enough to be indexed and quoted directly, while 7 remain tier C and are kept for search coverage. Forced degradation on the parent tells you which of these materials a method will actually encounter: hydrolytic stress generates the amide and ester cleavage products, oxidative stress generates the N-oxides and hydroxylated analogues, and photolytic stress generates the ring rearrangements. A standard that is not on that list is usually a process impurity, and it is controlled by the route rather than by the formulation. For a laboratory setting specifications, the workable sequence is to fix the impurity list from the monograph and the degradation study first, and only then to source the standards, because the list determines which materials are worth holding.

Sources: DailyMed (US NLM) - TOLMETIN SODIUM TABLET [CHARTWELL RX, LLC].

15 reference standards related to Tolmetin held in the RSSE catalogue — pharmacopoeial impurities, non-compendial impurities, metabolites and labelled analogues where available.

In this group: 9 impurity reference standards · 2 stable isotope labelled standards · 1 multi-component standard · 1 fine chemical. CAS numbers are listed for 15 of 15; 15 entries carry a structure drawing.

On this page

15 reference standards

All entries — structure, identifiers and pack sizes

15 reference standards

Frequently asked

How many Tolmetin-related reference standards do you hold?
15 standards are listed on this page as of the latest catalogue build. CAS numbers are published for 15 of them and 15 entries carry a structure drawing. The catalogue is extended as new lots are released.
Can you supply a Tolmetin impurity that is not listed here?
Yes. Non-compendial impurities can be quoted from a structure — a CAS number is not required. Send the structure, a SMILES string or the parent drug substance with your enquiry and we will come back with availability.
What documentation is supplied with Tolmetin impurities?
Every lot ships with its own certificate of analysis. The certificate records the catalogue number, the batch number, the tests performed, the specification applied and the result obtained for that lot. A safety data sheet is supplied with the shipment.
Do you publish prices or a lead time for Tolmetin impurities?
No price list is published: quotations are prepared per enquiry, because availability and packing depend on the lot and the quantity you need. Send the catalogue number and the quantity and a technical contact will answer with availability and a quotation.

Cannot find the impurity you need? Non-compendial impurities can be quoted from a structure — a CAS number is not required. Write to sales@rssechem.com.