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Proguanil impurities and related standards

Proguanil is held here as a working collection of 22 reference materials across 9 CAS numbers. Within the range, the lettered series reaches F. and 2 EP-designated impurities are named explicitly 7 of the entries are impurity-type materials of the parent, 8 are salt or counter-ion variants and 3 carry a deuterium label and 2 are nitrosamine analogues. 9 entries carry a verified structure drawing, a coverage of 41%; the rest are listed without a structure rather than with an unverified one. 9 of them sit in tier A or B, meaning the data behind the page is complete enough to be indexed and quoted directly, while 13 remain tier C and are kept for search coverage. Method transfer is the usual reason a laboratory needs the whole set rather than a few members: specificity has to be demonstrated against every impurity that could plausibly co-elute, and a spiked solution prepared from the actual standards is the accepted way to do it. For a laboratory setting specifications, the workable sequence is to fix the impurity list from the monograph and the degradation study first, and only then to source the standards, because the list determines which materials are worth holding.

Sources: DailyMed (US NLM) - ATOVAQUONE AND PROGUANIL HYDROCHLORIDE TABLET, FILM COATED [GOLDEN STATE MEDICAL SUPPLY, INC.].

9 reference standards related to Proguanil held in the RSSE catalogue — pharmacopoeial impurities, non-compendial impurities, metabolites and labelled analogues where available.

In this group: 2 general reference standards · 2 impurity reference standards · 2 fine chemicals · 2 stable isotope labelled standards. CAS numbers are listed for 9 of 9; 9 entries carry a structure drawing.

On this page

9 reference standards

All entries — structure, identifiers and pack sizes

9 reference standards

Frequently asked

How many Proguanil-related reference standards do you hold?
9 standards are listed on this page as of the latest catalogue build. CAS numbers are published for 9 of them and 9 entries carry a structure drawing. The catalogue is extended as new lots are released.
Can you supply a Proguanil impurity that is not listed here?
Yes. Non-compendial impurities can be quoted from a structure — a CAS number is not required. Send the structure, a SMILES string or the parent drug substance with your enquiry and we will come back with availability.
What documentation is supplied with Proguanil impurities?
Every lot ships with its own certificate of analysis. The certificate records the catalogue number, the batch number, the tests performed, the specification applied and the result obtained for that lot. A safety data sheet is supplied with the shipment.
Do you publish prices or a lead time for Proguanil impurities?
No price list is published: quotations are prepared per enquiry, because availability and packing depend on the lot and the quantity you need. Send the catalogue number and the quantity and a technical contact will answer with availability and a quotation.

Cannot find the impurity you need? Non-compendial impurities can be quoted from a structure — a CAS number is not required. Write to sales@rssechem.com.