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Probenecid impurities and related standards

Probenecid is held here as a working collection of 32 reference materials across 21 CAS numbers. Within the range, numbered impurities go up to 10. and 1 EP-designated impurities are named explicitly 17 of the entries are impurity-type materials of the parent, 1 are salt or counter-ion variants and 2 carry a deuterium label and 1 are nitrosamine analogues. 19 entries carry a verified structure drawing, a coverage of 59%; the rest are listed without a structure rather than with an unverified one. 19 of them sit in tier A or B, meaning the data behind the page is complete enough to be indexed and quoted directly, while 13 remain tier C and are kept for search coverage. Relative response factors are what decide whether a percentage on a chromatogram means anything. Impurities that lack a chromophore, or whose ultraviolet maximum sits away from the detection wavelength used for the parent, under-respond by a factor that has to be established with a solution of the standard itself rather than assumed. For a laboratory setting specifications, the workable sequence is to fix the impurity list from the monograph and the degradation study first, and only then to source the standards, because the list determines which materials are worth holding.

Sources: DailyMed (US NLM) - PROBENECID AND COLCHICINE TABLET [REMEDYREPACK INC.].

20 reference standards related to Probenecid held in the RSSE catalogue — pharmacopoeial impurities, non-compendial impurities, metabolites and labelled analogues where available.

In this group: 10 impurity reference standards · 8 fine chemicals · 1 drug metabolite standard · 1 stable isotope labelled standard. CAS numbers are listed for 20 of 20; 20 entries carry a structure drawing.

On this page

20 reference standards

All entries — structure, identifiers and pack sizes

20 reference standards

Frequently asked

How many Probenecid-related reference standards do you hold?
20 standards are listed on this page as of the latest catalogue build. CAS numbers are published for 20 of them and 20 entries carry a structure drawing. The catalogue is extended as new lots are released.
Can you supply a Probenecid impurity that is not listed here?
Yes. Non-compendial impurities can be quoted from a structure — a CAS number is not required. Send the structure, a SMILES string or the parent drug substance with your enquiry and we will come back with availability.
What documentation is supplied with Probenecid impurities?
Every lot ships with its own certificate of analysis. The certificate records the catalogue number, the batch number, the tests performed, the specification applied and the result obtained for that lot. A safety data sheet is supplied with the shipment.
Do you publish prices or a lead time for Probenecid impurities?
No price list is published: quotations are prepared per enquiry, because availability and packing depend on the lot and the quantity you need. Send the catalogue number and the quantity and a technical contact will answer with availability and a quotation.

Cannot find the impurity you need? Non-compendial impurities can be quoted from a structure — a CAS number is not required. Write to sales@rssechem.com.