Levocetirizine impurities and related standards
Levocetirizine is held here as a working collection of 84 reference materials across 16 CAS numbers. Within the range, numbered impurities go up to 68. 62 of the entries are impurity-type materials of the parent, 6 are salt or counter-ion variants. 20 entries carry a verified structure drawing, a coverage of 24%; the rest are listed without a structure rather than with an unverified one. 20 of them sit in tier A or B, meaning the data behind the page is complete enough to be indexed and quoted directly, while 64 remain tier C and are kept for search coverage. Forced degradation on the parent tells you which of these materials a method will actually encounter: hydrolytic stress generates the amide and ester cleavage products, oxidative stress generates the N-oxides and hydroxylated analogues, and photolytic stress generates the ring rearrangements. A standard that is not on that list is usually a process impurity, and it is controlled by the route rather than by the formulation. Where the impurity is a chiral species, the enantiomeric ratio belongs on the specification alongside the chemical purity, because an achiral method reports the two together as one peak.
Sources: DailyMed (US NLM) - LEVOCETIRIZINE DIHYDROCHLORIDE TABLET [PD-RX PHARMACEUTICALS, INC.].
24 reference standards related to Levocetirizine held in the RSSE catalogue — pharmacopoeial impurities, non-compendial impurities, metabolites and labelled analogues where available.
In this group: 11 impurity reference standards · 4 general reference standards · 3 fine chemicals · 3 pharmaceutical intermediates. CAS numbers are listed for 24 of 24; 24 entries carry a structure drawing.
On this page
24 reference standards
All entries — structure, identifiers and pack sizes
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Levocetirizine Hydrochloride
BACK ORDERRS-A012339 -
Cetirizine EP Impurity D DiHCl
IN STOCKRS-Z401LEQ -
Cetirizine EP Impurity G Monohydrochloride
CUSTOM SYNTHESISRS-L104001 -
(+)-1-[(4-Chlorophenyl) phenylmethyl] piperazine
IN STOCKRS-Z396WXU -
(4-Chlorophenyl)(2-((4-methylpiperazin-1-yl)methyl)phenyl)methanone
BACK ORDERRS-U111064 -
(4-Chlorophenyl)(phenyl)methanamine
IN STOCKRS-U006264 -
(R)-(+)-(4-chloro phenyl)phenyl methyl amine
IN STOCKRS-I009054 -
1,4-Piperazinediethylamine
IN STOCKRS-P017213 -
2-(2-Chloroethoxy)acetic acid
IN STOCKRS-C003028 -
2-(2-Chloroethoxy)acetonitrile
IN STOCKRS-Z401HV0 -
Benzhydrylamine hydrochloride
IN STOCKRS-U081831 -
N-((4-chlorophenyl)(phenyl)methyl)formamide
IN STOCKRS-P025302 -
N-(4-Methoxybenzyl)propan-2-amine
CUSTOM SYNTHESISRS-P025443 -
N-benzyl-4-chloroaniline
IN STOCKRS-Z401HCS -
Levocetirizine Impurity 1
IN STOCKRS-L104004 -
Levocetirizine Impurity 5
IN STOCKRS-L104007 -
Levocetirizine Impurity 10
IN STOCKRS-L104002 -
Levocetirizine Impurity 19
CUSTOM SYNTHESISRS-I001B1H -
Levocetirizine Impurity 49
BACK ORDERRS-I001A6Q -
N-Tosyl Cetirizine EP impurity A
IN STOCKRS-L104003 -
Levocetirizine Impurity 67
IN STOCKRS-L104005 -
Levocetirizine Impurity 68
CUSTOM SYNTHESISRS-L104006 -
Levocetirizine Impurity 76
BACK ORDERRS-I001ASY -
Levocetirizine Impurity 82
BACK ORDERRS-I001BKA
![Chemical structure of (+)-1-[(4-Chlorophenyl) phenylmethyl] piperazine](/structures/w4/UZKBSZSTDQSMDR-UHFFFAOYSA-N.webp?v=9)
24 reference standards
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