Ergotamine impurities and related standards
Ergotamine is held here as a working collection of 12 reference materials across 5 CAS numbers. Within the range, numbered impurities go up to 3. 5 of the entries are impurity-type materials of the parent, 1 are salt or counter-ion variants and 2 carry a deuterium label. 5 entries carry a verified structure drawing, a coverage of 42%; the rest are listed without a structure rather than with an unverified one. 4 of them sit in tier A or B, meaning the data behind the page is complete enough to be indexed and quoted directly, while 8 remain tier C and are kept for search coverage. The practical difficulty with a series of this size is not obtaining any one impurity but demonstrating that the set is complete. A validation package normally needs the specified impurities plus the unspecified ones above the reporting threshold, and the second group is where a catalogue either holds the material or does not. For a laboratory setting specifications, the workable sequence is to fix the impurity list from the monograph and the degradation study first, and only then to source the standards, because the list determines which materials are worth holding.
Sources: DailyMed (US NLM) - ERGOTAMINE TARTRATE AND CAFFEINE TABLET, FILM COATED [CINTEX SERVICES, LLC].
7 reference standards related to Ergotamine held in the RSSE catalogue — pharmacopoeial impurities, non-compendial impurities, metabolites and labelled analogues where available.
In this group: 2 impurity reference standards · 2 fine chemicals · 2 general reference standards · 1 api reference standard. CAS numbers are listed for 7 of 7; 7 entries carry a structure drawing.
On this page
7 reference standards
All entries — structure, identifiers and pack sizes
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Dihydroergotamine EP Impurity A
BACK ORDERRS-D316002 -
9,10-Dihydro-12’-methoxy Ergotamine
CUSTOM SYNTHESISRS-E206001 -
9,10-Dihydro-12’-methoxy Ergotamine discontinued
CUSTOM SYNTHESISRS-Z408RU3 -
Dihydro Ergotamine Ring-opened Acid
BACK ORDERRS-E206003 -
Ergotamine for system suitability-* prec (Y0001851)
CUSTOM SYNTHESISRS-E206002
7 reference standards
Frequently asked
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Cannot find the impurity you need? Non-compendial impurities can be quoted from a structure — a CAS number is not required. Write to sales@rssechem.com.

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