Chlorthalidone impurities and related standards
Chlorthalidone is held here as a working collection of 19 reference materials across 8 CAS numbers. Within the range, 1 EP-designated impurities are named explicitly. 8 of the entries are impurity-type materials of the parent, 2 carry a deuterium label. 8 entries carry a verified structure drawing, a coverage of 42%; the rest are listed without a structure rather than with an unverified one. 8 of them sit in tier A or B, meaning the data behind the page is complete enough to be indexed and quoted directly, while 11 remain tier C and are kept for search coverage. Forced degradation on the parent tells you which of these materials a method will actually encounter: hydrolytic stress generates the amide and ester cleavage products, oxidative stress generates the N-oxides and hydroxylated analogues, and photolytic stress generates the ring rearrangements. A standard that is not on that list is usually a process impurity, and it is controlled by the route rather than by the formulation. Co-elution with the parent is the trap in a series this closely related, so the useful certificate data are the retention time under a named method and the relative retention, not a purity figure alone.
Sources: DailyMed (US NLM) - CHLORTHALIDONE TABLET [UMEDICA LABORATORIES USA INC.].
8 reference standards related to Chlorthalidone held in the RSSE catalogue — pharmacopoeial impurities, non-compendial impurities, metabolites and labelled analogues where available.
In this group: 4 fine chemicals · 2 general reference standards · 2 impurity reference standards. CAS numbers are listed for 8 of 8; 8 entries carry a structure drawing.
On this page
8 reference standards
All entries — structure, identifiers and pack sizes
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Chlorthalidone
IN STOCKRS-U065489 -
2,3-dihydro-3-hydroxy-1H-isoindol-1-one
IN STOCKRS-Z401GLR -
2-(4-Chloro-3-nitrobenzoyl)benzoic Acid
IN STOCKRS-Z401LB4 -
Chlorthalidone Acid Methyl Ester Impurity
IN STOCKRS-C393002 -
Chlorthalidone RC 3
BACK ORDERRS-C393003 -
Chlorthalidone RC 4
BACK ORDERRS-C393004 -
Chlorthalidone RC 5
BACK ORDERRS-C393005 -
Chlorthalidone Impurity 7
IN STOCKRS-C393001
8 reference standards
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Cannot find the impurity you need? Non-compendial impurities can be quoted from a structure — a CAS number is not required. Write to sales@rssechem.com.