Afatinib impurities and related standards
58 reference standards related to Afatinib held in the RSSE catalogue — pharmacopoeial impurities, non-compendial impurities, metabolites and labelled analogues where available.
CAS numbers are listed for 58 of 58; 52 entries carry a structure drawing.
| Compound | CAS No. | Catalogue No. | Formula | MW |
|---|---|---|---|---|
| Afatinib impurity 36 | 1194097-41-0 | RS-A049003 | C7H5FN2O4 | 200.12 |
| Afatinib impurity 74 | 1259015-90-1 | RS-A049005 | C7H13NO2 | 143.18 |
| Afatinib impurity 73 | 137131-09-0 | RS-A049007 | C6H10BrNO | 192.05 |
| Afatinib Impurity 52 | 1401162-04-6 | RS-A049008 | C14H8ClF2N3 | 291.68 |
| Afatinib Impurity 90 | 1449430-45-8 | RS-A049009 | C14H8ClFN4O3 | 334.69 |
| Afatinib Impurity J | 1456696-14-2 | RS-A049010 | C18H22N4O4 | 358.39 |
| Afatinib Impurity 114 | 162012-67-1 | RS-A049011 | C14H7ClF2N4O2 | 336.68 |
| Afatinib impurity 17 | 162012-70-6 | RS-A049012 | C8H3ClFN3O2 | 227.58 |
| Afatinib Impurity I | 1637254-93-3 | RS-A049013 | C22H19BrClFN4O3 | 521.77 |
| Afatinib impurity D | 1680184-59-1 | RS-A049014 | C24H25ClFN5O3 | 485.94 |
| Afatinib Impurity 100 | 179552-73-9 | RS-A049015 | C14H7Cl2FN4O2 | 353.14 |
| Afatinib Impurity 101 | 184356-50-1 | RS-A049017 | C14H8ClFN4O2 | 318.69 |
| Afatinib Impurity 120 | 2044709-72-8 | RS-A049018 | C18H16F2N4O2 | 358.34 |
| Afatinib Impurity 122 | 2085843-51-0 | RS-A049019 | C22H23ClFN5O2 | 443.9 |
| Afatinib impurity 112 | 2121530-37-6 | RS-A049020 | C22H20ClFN4O4 | 458.87 |
| Afatinib Impurity 78 | 2168856-93-5 | RS-A049021 | C7H5FN2O4 | 200.12 |
| Afatinib Impurity 86 | 2170273-17-1 | RS-A049022 | C20H18ClF2N5O | 417.84 |
| Afatinib Impurity 89 | 2223677-58-3 | RS-A049023 | C22H20ClFN4O4 | 458.87 |
| Afatinib Impurity 119 | 2223677-60-7 | RS-A049024 | C19H16ClFN4O3 | 402.81 |
| Afatinib Impurity F | 2223677-62-9 | RS-A049025 | C24H25F2N5O3 | 469.48 |
| Afatinib Impurity SHO | 2223677-65-2 | RS-A049026 | C38H30Cl2F2N8O6 | 803.6 |
| Afatinib Impurity 51 | 2226537-61-5 | RS-A049027 | C14H7F3N4O2 | 320.23 |
| Afatinib impurity QJJ | 2323570-72-3 | RS-A049028 | C24H27ClFN5O4 | 503.95 |
| Afatinib impurity 75 | 2348580-72-1 | RS-A049029 | C7H14N2O | 142.2 |
| Afatinib Impurity 117 | 2413212-09-4 | RS-A049030 | C18H17ClN4O2 | 356.81 |
| Afatinib Impurity 24 | 2413212-25-4 | RS-A049032 | C24H26FN5O3 | 451.49 |
| Afatinib Impurity 121 | 2413212-27-6 | RS-A049033 | C27H27ClFN5O7 | 587.98 |
| Afatinib Impurity 26 | 2414260-31-2 | RS-A049034 | C26H32ClFN6O3 | 531.02 |
| Afatinib Impurity 116 | 2475094-95-0 | RS-A049035 | C14H8ClFN4O3 | 334.69 |
| Afatinib Impurity 31 | 2475095-51-1 | RS-A049036 | C14H9ClF2N4 | 306.7 |
| Afatinib Impurity 32 | 2475095-54-4 | RS-A049037 | C14H9Cl2FN4 | 323.15 |
| Afatinib Impurity 25 | 2475095-57-7 | RS-A049038 | C22H20ClFN4O5 | 474.87 |
| Afatinib Impurity 19 | 2512206-82-3 | RS-A049039 | C14H7Cl2FN4O2 | 353.14 |
| Afatinib Impurity 43 | 2636135-41-4 | RS-A049040 | C8H16N2O | 156.23 |
| Afatinib impurity 77 | 26404-20-6 | RS-A049041 | C5H7ClO3 | 150.56 |
| Afatinib impurity 53 | 2831861-00-6 | RS-A049042 | C14H7ClF2N4O2 | 336.68 |
| Afatinib impurity 111 | 3005278-77-0 | RS-A049043 | C22H23ClFN4O6P | 524.87 |
| Afatinib Impurity B | 314771-76-1 | RS-A049044 | C18H16ClFN4O2 | 374.8 |
| Afatinib Impurity A | 314771-88-5 | RS-A049045 | C18H14ClFN4O4 | 404.78 |
| Afatinib impurity 81 | 32224-01-4 | RS-A049046 | C6H11BrO3 | 211.05 |
| Afatinib impurity 66 | 350-30-1 | RS-A049047 | C6H3ClFNO2 | 175.54 |
| Afatinib impurity 72 | 37746-78-4 | RS-A049048 | C6H9BrO2 | 193.04 |
| Afatinib impurity 42 | 38090-53-8 | RS-A049049 | C4H7NO2 | 101.1 |
| Afatinib Impurity 88 | 402855-03-2 | RS-A049050 | C18H16ClFN4O2 | 374.8 |
| Afatinib Impurity 87 | 402855-07-6 | RS-A049051 | C18H14ClFN4O4 | 404.78 |
| Afatinib impurity 41 | 69169-63-7 | RS-A049052 | C7H10F3NO4 | 229.15 |
| Afatinib impurity 38 | 86728-85-0 | RS-A049053 | C6H11ClO3 | 166.6 |
| Afatinib impurity 80 | 90227-57-9 | RS-A049054 | C8H17NO3 | 175.23 |
| Afatinib impurity 44 | 915788-22-6 | RS-A049055 | C6H11NO2 | 129.16 |
| Afatinib Impurity 50 | 936558-43-9 | RS-A049056 | C14H7ClF2N4O2 | 336.68 |
| Afatinib impurity C | 945553-91-3 | RS-A049057 | C24H25ClFN5O3 | 485.94 |
| Afatinib impurity 45 | 99281-87-5 | RS-A049058 | C5H9NO2 | 115.13 |
| Afatinib Impurity 84 | 119136-85-5 | RS-A049002 | C10H21ClO2Si | 236.81 |
| Afatinib Impurity 5 | 179552-74-0 | RS-A049016 | C15H10ClFN4O3 | 348.72 |
| Afatinib impurity 69 | 106941-19-9 | RS-A049001 | C4H7ClO3 | 138.55 |
| Afatinib impurity 70 | 125781-04-6 | RS-A049004 | C4H7ClO2 | 122.55 |
| Afatinib Impurity 29 | 1260808-58-9 | RS-A049006 | C8H5ClFN3 | 197.6 |
| Afatinib Impurity 118 | 2413212-17-4 | RS-A049031 | C22H20ClFN4O3 | 442.87 |
Structures
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Afatinib impurity 36
COA per lot -
Afatinib impurity 74
COA per lot -
Afatinib impurity 73
COA per lot -
Afatinib Impurity 52
COA per lot -
Afatinib Impurity 90
COA per lot -
Afatinib Impurity J
COA per lot -
Afatinib Impurity 114
COA per lot -
Afatinib impurity 17
COA per lot
Frequently asked
How many Afatinib-related reference standards do you hold?
58 standards are listed on this page as of the latest catalogue build. CAS numbers are published for 58 of them and 52 entries carry a structure drawing. The catalogue is extended as new lots are released.
Can you supply an Afatinib impurity that is not listed here?
Yes. Non-compendial impurities can be quoted from a structure — a CAS number is not required. Send the structure, a SMILES string or the parent drug substance with your enquiry and we will come back with availability.
What documentation is supplied with Afatinib impurities?
Every lot ships with its own certificate of analysis. The certificate records the catalogue number, the batch number, the tests performed, the specification applied and the result obtained for that lot. A safety data sheet is supplied with the shipment.
Do you publish prices or a lead time for Afatinib impurities?
No price list is published: quotations are prepared per enquiry, because availability and packing depend on the lot and the quantity you need. Send the catalogue number and the quantity and a technical contact will answer with availability and a quotation.
Cannot find the impurity you need? Non-compendial impurities can be quoted from a structure — a CAS number is not required. Write to sales@rssechem.com.